Does anxiety more strongly impact females or males undergoing assisted reproduction?

BMC PsychiatryScott Cunningham MD PhD, et al. | September 20, 2022



Depression and/or anxiety in the female partner of an infertile couple both before and during assisted reproduction is associated with decreased pregnancy rates.

This study showed that males too have anxiety and depression before and during treatment, and a positive association exists between anxiety and depression in one partner and the other partner.

A total of 1247 infertile couples were enrolled in the study. The Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) were administered to the female and male partners before and during assisted reproduction.

The prevalence of anxiety before treatment was 13.5% and 8.7% among females and males undergoing assisted reproduction, respectively. The prevalence of depression before treatment was 9.4% and 7.9% among females and males undergoing assisted reproduction, respectively.

The SAS and SDS scores decreased during treatment.

The SAS and SDS scores were positively associated between females and males, and correlated among individuals. Anxiety was positively associated with depression and vice versa. Among infertile couples, greater than one-fourth (25.9%) of partners had significant SAS and/or SDS scores.

Risk factors for anxiety in females included no children, unemployment, and less education.

Read the full article on BMC Psychiatry