Diagnostic value of microRNAs for depression

Journal of Psychiatric ResearchScott Cunningham MD PhD, et al. | November 29, 2022



Although the pathogenesis of depression has not been elucidated, evidence is accumulating to support an interplay between epigenetic, genetic, and environmental factors. The current study added to the growing body of literature by showing miRNAs have good sensitivity and specificity as biomarkers for clinical depression.

The literature was searched for studies involving miRNA expression in patients diagnosed with depression.

The sensitivity and specificity of miRNAs for depression were 82% and 76%, respectively.